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Case Studies in Ophthalmology

Cases for the Ophthalmology Clerkship

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Case #48 Ophthalmia Neonatorium


History

Between the 5th and 6th postpartum days, this infant developed a purulent conjunctivitis with lid swelling.

Photo #1

A photomicrograph of a scraping of the patient’s conjunctival epithelium stained with Giemsa stain showed intracytomplasmic inclusions.

Photo #2


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Question #1

Discuss the historical significance of ophthalmia neonatorum.

Question #2

Discuss the more common as well as the most serious infectious causes of ophthalmia neonatorum.

Question #3

Discuss the reasons for making a specific etiologic diagnosis and the appropriate studies to do so.

Question #4

What is Crede prophylaxis and what are its short-comings?

Question #5

Discuss the appropriate treatment for the currently most common cause of ophthalmia neonatorum.

 

References

Raucher HS, Newton MJ: New issues in the prevention and treamentof ophthalmia neonatorum. Ann Ophthalmol 1983; 15:1004-1009.

Sandstrom KI et al: Microbial causes of neonatal conjunctivitis. J Pediatr 1984: 105:706-11.

Rapoza PA et al: Epidemiology of neonatal conjunctivitis. Ophthalmology 1986; 93:456-461.

Harrison HR: Chlamydial ophthalmia neonatorum. The dilemma of diagnosis and treatment. AJDC 1985; 139:550-551

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