Selecting Intraocular Lens (IOL) Power

Ridley's post op refraction in 1949 was -24.0 +6.0 x30 - your patients will expect better
Four things you need to know to calculate correct IOL power:

1) Desired postoperative SE
Usually -0.5 to -1.00 is the plan. Why?
if you are left myopic post op. someplace in front of your head is in focus
-1.00 gets you about 20/40 at far and you can see well at mid distance
A spectacle overcorrection of -1.00 will nearly eliminate induced IOL mag.
Sometimes however you may not want a SE of -1.00
if the other eye is stable (post op or no cataract) and you want to match it
patient prefers to have 20/20 at far without correction (good luck)

2) The length of the eye
AEL device uses ultrasound to estimate the length of the eye
Measure both eyes
Remeasure if     greater than 0.3 mm difference between eyes
AEL < 22 or > 25
Full of potential error, pushing too hard, not axial, etc...
Error on device at VA can be, as high as +/- 0.5 mm. according to Dr. Ossoinig
With AEL < 22 or > 25 consider sending to echo for immersion beware of staphyloma

3) The power of the cornea
Keratometric measurement of both eyes -- should be about the same
Remeasure if     greater than 1 diopter difference between eyes
K ave < 40 or > 47
mires are irregular

4) The post operative position of the IOL
The more anterior the IOL is placed the less power the IOL needs for emmetropia
Goal is to place a posterior chamber (PC) lens
These can end up in the bag (best) or sulcus (anterior to ant. capsule)
Inadvertent placement in the sulcus creates a 0.75 d myopic shift
Always plan to have available anterior chamber (AC) lenses
These are placed anterior to the iris w/haptics that settle into the angle
These are used when the posterior capsule is not agreeable to holding an IOL
When too small they can tilt and when too large they can hurt

Estimating the IOL power for emmetropia:

Formulas started with a theoretical model by Fydorov, Collenbrander et all, 1970s
Based on geometric optics
Power = N/(AEL-ACD) - N/(N/K-ACD)
where:     Power is the expected power of IOL for emmetropia post op
N is the aqueous and vitreous refractive index
ACD is the post operative depth of the IOL
AEL is the axial eye length as measured via an ultrasound device
Ave-K is average of the two keratometric axes

But you don't know the ACD or post operative depth of the lens pre op!

Useful Formulas use regression analysis or other tricks to estimate ACD
1) SRK    
Power = A-constant - 2.5(AEL) - 0.9(Ave-K)

Classic regression formula develped in 1980 by Sanders, Retzlaff, and Kraff
where: A-constant is a parameter of the type of lens and ACD
eg.     PC lens -- Alcon acrysoft A constant of 118.9
AC lens -- Alcon MTA series A constant of 115.3

note that an error of x in axial eye length results in an error of 2.5x in IOL power
falls apart in predictive value with eyes w/AEL < 22 and > 24.5

2) Other algorithms
AEL device has many algorithms to choose from to give power for both PC and AC lenses
Some also use ant chamber depth to estimate IOL power
Error is greatest with with high myopes and high hyperopes
Estimate the power for both the AC and the PC lens compare several formulas
High myopes end up more myopic and high hyperopes end up more hyperopic post op than predicted

Selecting the IOL power for your patient
The SRK computes the lens power for emmetropia; but, you probably want -1.00
you can use the AEL device printout to find the lens for any desired post op. SE
roughly a change of the IOL from the emmetropic value of 1.4 results in SE change of 1.0
eg. SRK gives 19 diopters for emmetropia, about 20.5 will give -1.00 SE post op.

If your estimated IOL power is unusual you are probably wrong
Double check your calculations and when applicable look at experience with other eye's IOL
ask yourself was the patient very myopic or hyperopic as a young person (eg in the big war)
then if convinced that the calculations are right, make sure the lens is stocked


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