Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV)
Contributor: Jesse Vislisel, MD
Photographer: Cindy Montague, CRA
Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) is a hereditary autoimmune disorder of the eye caused by mutations in the CAPN5 gene. It is characterized by abnormal retinal pigmentation, retinal and iris neovascularization, panuveitis, vitreous hemorrhage, intraocular fibrosis and membrane formation, and tractional retinal detachment. This photo shows diffuse epiretinal membranes and fibrosis in a patient with ADNIV.
Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa are licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.