EyeRounds Online Atlas of Ophthalmology
Contributor: Matt Ward, MD, The University of Iowa
Infectious Crystalline Keratopathy
This an indolent corneal infection classically occuring in the absence of an epithelial defect in corneal transplants on chronic steroid therapy. It has a frost-like crystalline pattern. It is typically caused by alpha-hemolytic streptococcus species such as Viridans. In this case, this patient was on chronic mild steroid drops (fluormethalone) for treatment of severe, recalcitrant blepharitis and ocular surface disease. ICK is difficult to treat medically and may require debridement either by hand or with an excimer laser.
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