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Ophthalmology and Visual Sciences

Acanthamoeba keratitis

Acanthamoeba keratitis

Category(ies): Cornea
Contributor: Jesse Vislisel, MD, Jordan Graff, MD, Meagan Seay, DO
Photographer: Brice Critser, CRA

Acanthamoeba keratitis is a rare parasitic infection of the cornea that primarily occurs in contact lens wearers. The infection may be limited to the epithelium in its early stages, resulting in epithelial dendrites and punctate epitheliopathy. Later stromal involvement classically results in a partial or complete paracentral ring infiltrate, radial perineuritis, and pain out of proportion to the appearance on exam. Scleritis and uveitis may also be present.


Krachmer, Jay H., Mark J. Mannis, Edward J. Holland. Cornea. St. Louis: Mosby, 2011.

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