EyeRounds Online Atlas of Ophthalmology

Contributor:
William Charles Caccamise Sr,MD, Retired Clinical Prof of Ophthalmology-U of Rochester School of Medicine and Dentistry

Category: Glaucoma
Diagnosis: adrenochrome due to epinephrine

Image Comments:

This photograph was taken in 1964. At that time P2E1 - 2% pilocarpine with 1% epinephrine - was commonly used in treating open-angle glaucoma.Oxidation products frequently caused pigmented conjunctival deposits -sometimes called adrenochromes In the photograph a minute brown dot is seen - a typical pigment deposit due epinephrine in the glaucoma drops.There is a pinpoint spot about 2 to 3 mms from the upper lid margin at 3 o'clock that must be evaluated under the slit-lamp to determine whether it is an incipient adrenochrome.

 

 

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