University of Iowa Health Care

Ophthalmology and Visual Sciences

EyeRounds Online Atlas of Ophthalmology

Contributor: William Charles Caccamise, Sr, MD,, Retired Clinical Professor of Ophthalmology, University of Rochester School of Medicine and Dentistry

*Dr. Caccamise has very generously shared his images of patients taken while operating during the "eye season" in rural India as well as those from his private practice during the 1960's and 1970's. Many of his images are significant for their historical perspective and for techniques and conditions seen in settings in undeveloped areas.

Category: Glaucoma / Iris

Adrenochrome due to epinephrine

adrenochrome due to epinephrine

This photograph was taken in 1964. At that time P2E1 - 2% pilocarpine with 1% epinephrine - was commonly used in treating open-angle glaucoma. Oxidation products frequently caused pigmented conjunctival deposits -sometimes called adrenochromes. In the photograph a minute brown dot is seen - a typical pigment deposit due epinephrine in the glaucoma drops.There is a pinpoint spot about 2 to 3 mms from the upper lid margin at 3 o'clock that must be evaluated under the slit-lamp to determine whether it is an incipient adrenochrome.

Creative Commons License
Ophthalmic Atlas Images by, The University of Iowa are licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.

last updated: 02-08-2008