EyeRounds Online Atlas of Ophthalmology
Contributor:
Jordan M. Graff, MD, University of Iowa
Category: Pediatrics
Diagnosis: coloboma, Iris

Image Comments:
Typical coloboma of the iris, seen here as an inferonasal keyhole defect in the iris in both eyes (right and left eyes shown as if patient is facing the examiner with the nose removed).
Typical colobomas of the iris, as shown here, are caused by failure of the embryonic optic vessicle to close. The ciliary body, choroid, retina, and optic nerve may thus also be involved in patients with iris coloboma.
Iris colobomas can be associated with almost many types of chromosomal abnormalities and syndromes
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