University of Iowa Health Care

Ophthalmology and Visual Sciences

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Salzmann nodular corneal degeneration

Contributor: Jesse Vislisel, MD

Photographer: Brice Critser, CRA

Salzmann nodular degeneration is a non-inflammatory corneal degeneration, often secondary to an old, chronic keratitis. The nodules result when Bowman membrane is replaced by hyaline and fibrillar material. They are elevated and gray-white to blue-white in color. They are classically round and located in the mid-periphery, though they can be more extensive as seen here. Note the iron lines along the leading edge of the nodules secondary to tear film stasis.

click images for higher resolution

right eye:

Salzman nodular corneal degenerationSalzman nodular corneal degenerationSalzman nodular corneal degeneration

left eye:

Salzman nodular corneal degenerationSalzman nodular corneal degenerationSalzman nodular corneal degeneration


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last updated: 10/28/2013
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