Salzmann nodular corneal degeneration
Contributor: Jesse Vislisel, MD
Photographer: Brice Critser, CRA
Salzmann nodular degeneration is a non-inflammatory corneal degeneration, often secondary to an old, chronic keratitis. The nodules result when Bowman membrane is replaced by hyaline and fibrillar material. They are elevated and gray-white to blue-white in color. They are classically round and located in the mid-periphery, though they can be more extensive as seen here. Note the iron lines along the leading edge of the nodules secondary to tear film stasis.
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