University of Iowa Health Care

Ophthalmology and Visual Sciences

EyeRounds.org

Sorsby macular dystrophy

Contributor: Jesse Vislisel, MD

Photographer: Stefani Karakas, CRA

Sorsby macular dystrophy is an autosomal dominant condition caused by a mutation in the TIMP3 gene. Patients with this condition typically maintain normal acuity until their 40's when they develop severe, bilateral choroidal neovascular membranes. The macular lesions later have a "pseudo-inflammatory" appearance with geographic atrophy and dense clumps of black pigmentation, as seen in these photographs.

(click either image for higher resolution)

right eye

lefteyeleft eye


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Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa are licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.

last updated: 10/24/2013
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