ITGB1 Cd29 Choroid
Dividing Endothelial Cells
Endothelial Cell Migration
Choroid Retina ICAM2
Endothelial Cell Actin
Immunofluorescence image of beta-1 integrin/CD29 labeling in blood vessels of the choriocapillaris (CC). The yellow autofluorescence of the retinal pigment epithelium (RPE) is due to the accumulation of lipofuscin, which occurs in aging eyes.
Scanning electron micrograph of dividing endothelial cells.
Histology of a druse (plural, drusen) from a human donor eye. Drusen are presymptomatic risk factors for AMD that develop between the retinal pigment epithelium(RPE) and its blood supply, the choroiocapillaris (CC).
Drusen from a human donor eye with AMD, labeled with an antibody directed against terminal complement complex C5b-9 (green fluorescence) illustrates the role of immune-mediated processes in AMD. For details see Mullins et al., 2000, FASEB J, 14(7):835-46; Skeie et al., 2010, IOVS in press.
Immunohistochemical labeling of cone photoreceptor cells from a human retina. Nuclei are stained blue with a DNA-binding probe.
Scanning electron micrograph of a migrating choroidal endothelial cell. These cells become activated by elastin, which may be an important factor in macular degeneration. For details see Skeie and Mullins, Invest Ophthalmol Vis Sci 2008 49: 5574-80.
Localization of the endothelial cell adhesion molecule ICAM-2 (purple) in blood vessels of the retina and choroid.
Actin (green) staining of endothelial cells. Nuclei are labeled blue.