Microcornea is defined as a cornea less than 10 mm in diameter. It is thought that microcornea occurs secondary to an arrest in corneal development due to overgrowth of the tips of the optic cup. The differential diagnosis includes cornea plana, sclerocornea, nanophthalmos, and anterior microphthalmos.
The patient in this photograph has microcornea (corneal diameter 5 mm) associated with primary congenital glaucoma. The condition is associated with an increased risk of glaucoma and patients are usually hyperopic.
Contributor: William Charles Caccamise, Sr, MD, Retired Clinical Assistant Professor of Ophthalmology, University of Rochester School of Medicine and Dentistry
*Dr. Caccamise has very generously shared his images of patients taken while operating during the "eye season" in rural India as well as those from his private practice during the 1960's and 1970's. Many of his images are significant for their historical perspective and for techniques and conditions seen in settings in undeveloped areas.
Narumi Y, Nishina S, Tokimitsu M, et al. Identification of a novel missense mutation of MAF in a Japanese family with congenital cataract by whole exome sequencing: a clinical report and review of literature. Am J Med Genet A. 2014;164A(5):1272-6.
Nischal KK. Corneal abnormalities. Pediatric ophthalmology and strabismus 2e. New York: Springer; 2002;391-429.