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Ophthalmology and Visual Sciences

Retinoblastoma

Retinoblastoma

Category(ies): Pathology
Contributor: Meagan Seay, DO and Nasreen Syed, MD

H&E of retinoblastoma
Retinoblastoma is a small, round, blue cell tumor. The pink areas are necroses.
H&E of retinoblastoma close-up showing Flexner-Wintersteiner rosettes
Flexner-Wintersteiner rosettes contain a central lumen. Homer Wright rosettes contain neurofibrillary tangles in the center.