Saturday, May 4
| Budd A. Tucker, PhD |
11:15 AM |
12:15 PM |
Using AMD patient iPSC-derived choroidal endothelial cells to evaluate disease pathology and develop an autologous cell replacement strategy |
Development of pluripotent stem cell-based platforms for disease modeling and therapies |
2 |
Education Course |
612 - Seattle Convention Center - Arch Building |
|
Presenter |
Budd A. Tucker |
Sunday, May 5
| Oliver W. Gramlich, PhD |
8:00 AM |
9:45 AM |
A0299: Correlation between visual biomarkers and motor-sensory deficits in a model of multiple sclerosis |
Neuro-Ophthalmology |
105 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Eye Movements/Strabismus/Amblyopia/Neuro-Ophthalmology |
Presenter |
Oliver W. Gramlich, Benjamin W. Elwood, Jeffrey Anders, Randy H. Kardon |
Sunday, May 5
| Wisam Najdawi |
1:00 PM |
2:45 PM |
A0190: Resident- versus Faculty-Placed Toric Intraocular Lens Outcomes |
Cataract surgery: Outcomes and epidemiology |
129 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Lens |
Presenter |
Wisam Najdawi, Zachary Mortensen, Tirth Shah, Thomas Oetting |
Sunday, May 5
| Jordan Mayberry |
1:00 PM |
2:45 PM |
A0235: Contribution of CD4 and CD8 cells to retinal ganglion cell loss in glaucoma |
Inflammatory factors contributing to ocular diseases |
130 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Immunology/Microbiology |
Presenter |
Jordan Mayberry, Huilan Zeng, Markus H. Kuehn |
Sunday, May 5
| Kelly Mulfaul, PhD |
1:00 PM |
2:45 PM |
B0237: Complement injury and CRP stress alter inflammatory cytokine secretion in AMD iPSC derived choroidal endothelial cells |
AMD: Mechanisms and preclinical studies |
135 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Kelly Mulfaul, Samantha G. Schwarte, Megan J. Riker, Brynnon E. Harman, Edwin M. Stone, Budd A. Tucker, Robert F. Mullins |
Sunday, May 5
| Arlene Drack, MD |
3:15 PM |
5:00 PM |
Moderator |
Current clinical trials and novel approaches for treatment of genetic disorders |
152 |
Paper Session |
Tahoma 3 - Seattle Convention Center - Arch Building |
Biochemistry/Molecular Biology |
Moderator |
|
Sunday, May 5
| Riley Filister |
3:15 PM |
5:00 PM |
B0055: Topical Dorzolamide Prevents Increases in Retinal Vascular Resistance Following Sympathetic Activation dynamics |
Neuroprotection, blood flow, ischemia-reperfusion and aqueous humor |
160 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Physiology/Pharmacology |
Presenter |
Riley Filister, Edward Linton, Randy H. Kardon |
Sunday, May 5
| Nicholas E. Stone, PhD |
3:45 PM |
4:00 PM |
Device-free isolation of photoreceptors from patient stem cell derived retinal organoids |
Advances in stem cell and organoid models of retinal development and disease |
141 |
Paper Session |
6BC - Seattle Convention Center - Arch Building |
Retinal Cell Biology |
Presenter |
Nicholas Edwin Stone, Laura R. Bohrer, Nathaniel Kevin Mullin, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker |
Sunday, May 5
| Seongjin Seo, PhD |
4:45 PM |
5:00 PM |
Delivering large genes using adeno-associated virus (AAV) and the CRE-lox DNA recombination system |
Current clinical trials and novel approaches for treatment of genetic disorders |
152 |
Paper Session |
Tahoma 3 - Seattle Convention Center - Arch Building |
Biochemistry/Molecular Biology |
Presenter |
Seongjin Seo, Poppy Datta, Kun Do Rhee, Rylee J. Staudt, Jacob Thompson, Ying Hsu, Salma Hassan, Tyler Rankin, Arlene V. Drack |
Monday, May 6
| Erin R. Burnight, PhD |
8:30 AM |
10:15 AM |
A0006: A dual AAV vector approach for the treatment of ABCA4-associated retinal disease |
Stem cells and therapeutic development |
215 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Erin R. Burnight, Luke A. Wiley, Dalyz Ochoa, Katayoun Varzavand, Seongjin Seo, Ian Han, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker |
Monday, May 6
| Laura R. Bohrer, PhD |
8:30 AM |
10:15 AM |
A0007: Transplantation of cGMP compliant iPSC-derived retinal progenitor cells |
Stem cells and therapeutic development |
215 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Laura R. Bohrer, Luke A. Wiley, Allison T. Wright, Louisa Affatigato, Robert F. Mullins, Edwin M. Stone, Ian Han, Budd A. Tucker |
Monday, May 6
| Narendra Pandala, PhD |
8:30 AM |
10:15 AM |
A0008: iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD |
Stem cells and therapeutic development |
215 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Narendra Pandala, Ian Han, Emily Meyering, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker |
Monday, May 6
| Jessica A. Cooke, PhD |
8:30 AM |
10:15 AM |
A0009: Retinal differentiation propensity is linked to pluripotency factor localization and donor cell epigenetic memory |
Stem cells and therapeutic development |
215 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Jessica A. Cooke, Nathaniel Kevin Mullin, Douglas B. Critser, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker |
Monday, May 6
| Renato Jensen |
3:00 PM |
4:45 PM |
A0069: miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa |
Treatment strategies for inherited retinal disease |
245 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Renato Jensen, Lorena Haefeli, Luke A. Wiley, Colleen Stein, Jessica L. Fick, Malia Collins, Robert F. Mullins, Ian Han, Edwin M. Stone, Ryan Boudreau, Budd A. Tucker |
Monday, May 6
| Lorena Haefeli, MD |
3:00 PM |
4:45 PM |
A0070: Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak-deficient rat model of photoreceptor degeneration |
Treatment strategies for inherited retinal disease |
245 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Lorena Haefeli, Luke A. Wiley, Cathryn Cranston, Heather Daggett, Ian Han, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker |
Monday, May 6
| Todd E. Scheetz, MS, PhD |
3:00 PM |
3:15 PM |
Functional evaluation of DNA variations associated with exfoliation syndrome in the LOXL1 locus |
Zooming in on genes and their influence on disease |
241 |
Paper Session |
Chelan 2 - Seattle Convention Center - Arch Building |
Genetics Group |
Presenter |
Todd E. Scheetz, Floyd L. Evans, Benjamin R. Roos, John H. Fingert |
Tuesday, May 7
| Timothy Boyce, MD |
8:30 AM |
10:15 AM |
A0178: Progressive Expansion of Chorioretinal Atrophy in Placoid-Spectrum Disease |
Clinical and experimental advances in the analysis of ocular inflammation |
317 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Immunology/Microbiology |
Presenter |
Timothy Boyce |
Tuesday, May 7
| Vincent Michael Patella |
8:30 AM |
10:15 AM |
A0242: Reference Database for a Novel Binocular Visual Function Analyzer |
Assessing the visual system I - Binocular vision, eye movements, motion, and color |
319 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Visual Psychophysics/Physiological Optic |
Presenter |
Vincent Michael Patella, Nevin W. El-Nimri, John G. Flanagan, Timothy Bossie, Derek Ho, Mayra Tafreshi, Michael A. Chaglasian, David Kasanoff, Sasan Moghimi, Takashi Nishida, Murray Fingeret, Robert N. Weinreb |
Tuesday, May 7
| Kristin Davis |
8:30 AM |
10:15 AM |
A0245: Nystagmus recordings and correlation with underlying diagnosis in children |
Assessing the visual system I - Binocular vision, eye movements, motion, and color |
319 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Visual Psychophysics/Physiological Optic |
Presenter |
Kristin Davis, Alina Valentina Dumitrescu, Veronica Peotta-Jacobsen, Joel Vandelune |
Tuesday, May 7
| Noor-Us-Sabah Ahmad, MD |
9:45 AM |
10:00 AM |
Ocular Blood Flow Decreases During Hemodialysis |
Understanding and modulating ocular physiology: Insights into aqueous humor dynamics, intraocular pressure, and blood flow |
310 |
Paper Session |
Yakima 1 - Seattle Convention Center - Arch Building |
Physiology/Pharmacology |
Presenter |
Noor-Us-Sabah Ahmad, Julie Nellis, Jui-Kai Wang, Noriyoshi Takahashi, Edward Linton, Randy H. Kardon |
Tuesday, May 7
| Christine W. Sindt, OD, FAAO |
1:15 PM |
3:00 PM |
A0301: Evidence Based Metrics for Selection of Wavefront Guided (WFG)/Higher Order Aberration (HOA) Correction Scleral Lens Candidates |
Optics, imaging, and retinal function |
339 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Visual Psychophysics/Physiological Optic |
Presenter |
Christine W. Sindt, Marcus Noyes, Daniel R. Neal, Xifeng Xiao |
Tuesday, May 7
| Elliott H. Sohn, MD, FASRS |
1:15 PM |
3:00 PM |
B0454: Inflammatory phenotype associated with high risk MMP9 genotype in neovascular AMD |
AMD: Translational studies |
349 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retina |
Presenter |
Elliott H. Sohn, Zeb Zacharias, kyungmoo lee, Chirantan Mukhopadhyay, Razek Coussa, Ian Han, Todd E. Scheetz, John H. Fingert, Edwin M. Stone, jon houtman, Milan Sonka |
Tuesday, May 7
| S. Scott Whitmore, PhD |
1:15 PM |
3:00 PM |
Moderator; Poster Range: B0400-B0441 |
AI in the Retina II |
348 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retina |
Moderator |
|
Tuesday, May 7
| Hansen Dang |
3:30 PM |
5:15 PM |
B0656: Hand motion tracking of faculty and residents during corneal suture throw |
Teaching, training and education |
374 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Clinical/Epidemiologic Research |
Presenter |
Hansen Dang, Noor-Us-Sabah Ahmad, Ryan Neuhaus, Andrew E. Pouw |
Tuesday, May 7
| John H. Fingert, MD, PhD |
3:30 PM |
5:15 PM |
B0687: METTL23 mutations and normal tension glaucoma (NTG) in a United States population |
Genetic variation underlying disease |
375 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Genetics Group |
Presenter |
John H. Fingert, Mallory R. Tollefson, Benjamin R. Roos, Erin Boese, Andrew E. Pouw, Edwin M. Stone, Michael Schnieders, Todd E. Scheetz |
Wednesday, May 8
| S. Scott Whitmore, PhD |
10:30 AM |
12:15 PM |
A0173: A computational model of retinal atrophy and visual acuity: applications to macular degeneration |
Retina miscellaneous II |
417 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retina |
Presenter |
S Scott Whitmore, Douglas B. Critser, Edwin M. Stone, Ian Han |
Wednesday, May 8
| Nathaniel K. Mullin |
10:30 AM |
12:15 PM |
B0203: The NR2E3 variant c.932G>A (p.Arg311Gln) creates an alternative splice acceptor leading to an in-frame deletion of 186 nucleotides |
Stem cell models of retinal development and disease |
419 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Nathaniel Kevin Mullin, Laura R. Bohrer, Kristin R. Anfinson, Jeaneen L. Andorf, Robert F. Mullins, Budd A. Tucker, Edwin M. Stone |
Wednesday, May 8
| Emma Mae Navratil |
2:15 PM |
4:00 PM |
A0021: The role of nicotinamide N-methyltransferase in choroidal endothelial cells: possible role in macular neovascularizationChoroidal vasculature and neovascularization |
Choroidal vasculature and neovascularization |
437 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Emma Mae Navratil, Miles J. Flamme-Wiese, Adnan Khan, Xiuying Liu, Luke A. Wiley, Edwin M. Stone, Budd A. Tucker, Robert F. Mullins |
Wednesday, May 8
| Merri-Grace Jones |
2:15 PM |
4:00 PM |
A0283: Type I interferon signaling shapes B cell phenotype and pathogenicity in the nonobese diabetic (NOD) mouse model of Sjögren's disease |
Immunological landscape in ocular health and diseases |
440 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Immunology/Microbiology |
Presenter |
Merri-Grace Jones, Ivy Debreceni, Scott Lieberman |
Wednesday, May 8
| Sarah Brumley |
2:15 PM |
4:00 PM |
A0470: Reduced abundance of trabecular meshwork stem cells in human donor eyes with POAG |
Outflow pathway and aqueous humor dynamics II |
444 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Glaucoma |
Presenter |
Sarah Brumley, Markus H. Kuehn |
Wednesday, May 8
| Maram El-Geneidy |
2:15 PM |
4:00 PM |
B0055: The Educational Efficacy of a Novel Interactive, Case-Based Educational Module for Prescribing Pediatric Spectacles |
Pediatric ophthalmology |
446 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Eye Movements/Strabismus/Amblyopia/Neuro-Ophthalmology |
Presenter |
Maram El-Geneidy, Margaret Strampe, Brett Johnson, Pavlina Kemp, Andrew E. Pouw |
Wednesday, May 8
| Giulia Steuernagel Del Valle, MD |
2:15 PM |
4:00 PM |
B0061: Correlation of Flash Visual Evoked Potentials with Visual Acuity and Goldmann Visual Fields in Pediatric Patients with Inherited Retinal Disorders |
Pediatric ophthalmology |
446 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Eye Movements/Strabismus/Amblyopia/Neuro-Ophthalmology |
Presenter |
Giulia Steuernagel Del Valle, Rose McGlauflin, Wanda L. Pfeifer, Arlene V. Drack |
Wednesday, May 8
| Ian C. Han, MD |
2:15 PM |
4:00 PM |
B0383: Development of chemically induced choroidal injury models for the study and treatment of AMD |
Retinal function testing and advanced therapies |
451 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retina |
Presenter |
Ian Han, Narendra Pandala, Lorena Haefeli, Mallory J. Lang, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker |
Thursday, May 9
| Bernardo Bach |
8:00 AM |
9:45 AM |
B0085: High-risk MMP9 genotype is associated with worse long-term change in PED width in treated eyes with neovascular AMD |
AMD-4 (clinical research) |
505 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retina |
Presenter |
Bernardo Bach, Thomas Martinez, Mary M. McCormick, Srinivas Chava, Benjamin Roos, Amy Wu, Kai Wang, Todd Scheetz, John H. Fingert, Elliott H. Sohn |
Thursday, May 9
| Alina V. Dumitrescu, MD, FACS |
8:00 AM |
9:45 AM |
Moderator, Poster Range: B0899-B0947 |
Gene and cell therapies and other novel therapeutics II |
515 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Biochemistry/Molecular Biology |
Moderator |
|
Thursday, May 9
| Edward F. Linton, MD |
8:00 AM |
9:45 AM |
B0111: Laser Speckle Flowgraphy Reveals Widespread Reductions in Ocular Blood Flow in Non-exudative Age-related Macular Degeneration Independent of Ocular Perfusion Pressure |
AMD-4 (clinical research) |
505 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retina |
Presenter |
Edward Linton, Noor-Us-Sabah Ahmad, Riley Filister, Jui-Kai Wang, Elliott H. Sohn, Randy H. Kardon |
Thursday, May 9
| Apurva Dusane |
8:00 AM |
9:45 AM |
B0347: Ripasudil liposomes with transferrin targeting for Fuchs endothelial corneal dystrophy |
Corneal endothelium: Dystrophies |
507 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Cornea |
Presenter |
Apurva Dusane, Sanjib Saha, Jessica M. Skeie, Hannah Shevalye, Tim Eggleston, Gregory A. Schmidt, Mark A. Greiner, Aliasger K. Salem |
Thursday, May 9
| Bryce Shonka |
8:00 AM |
9:45 AM |
B0361: SOD2 in Fuchs endothelial corneal dystrophy: Friend or foe? |
Corneal endothelium: Dystrophies |
507 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Cornea |
Presenter |
Bryce Shonka, Hannah Shevalye, Jessica M. Skeie, Tim Eggleston, Apurva Dusane, Naomi S. Greiner, Mark A. Greiner |
Thursday, May 9
| Lola Lozano |
8:00 AM |
9:45 AM |
B0879: Developing a molecular assay to predict hemangioblastoma phenotype severity in VHL disease |
Retinal degeneration |
514 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Retinal Cell Biology |
Presenter |
Lola Lozano, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker, Elaine Binkley |
Thursday, May 9
| Ying Hsu |
8:00 AM |
9:45 AM |
B0923: A candidate gene therapy vector delays vision loss in a mouse model of Bardet-Biedl Syndrome Type 10 |
Gene and cell therapies and other novel therapeutics II |
515 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Biochemistry/Molecular Biology |
Presenter |
Ying Hsu, Tyler Rankin, Brianna Lobeck, Tassos Georgiadis, Sophia Kleine Holthaus, Emily Kalmanek, Sarah Stanley, Jacob Thompson, Salma Hassan, Val Sheffield, Arlene V. Drack |
Thursday, May 9
| Lydia Yang |
11:45 AM |
1:30 PM |
B0736: Improvements in Documentation and Billing of Ophthalmology Diagnostic Testing |
Ophthalmology health and healthcare research |
534 |
Poster Session |
Exhibit Hall - Seattle Convention Center |
Clinical/Epidemiologic Research |
Presenter |
Lydia Yang, Molly Kuhn, Andrew E. Pouw |
Thursday, May 9
| Honghai Zhang |
12:15 PM |
12:30 PM |
Open Access Accelerated Deep Learning Model in Ophthalmology: Choroidal Layer SegmentationMachine learning for image segmentation |
Machine learning for image segmentation |
526 |
Paper Session |
Tahoma 2 - Seattle Convention Center - Arch Building |
Multidisciplinary Ophthalmic Imaging Group |
Presenter |
Honghai Zhang, Zhi Chen, Andreas Wahle, Bernardo Bolzani Bach, Ted Maddess, Elliott H. Sohn, Milan Sonka |
Thursday, May 9
| Jui-Kai Wang, PhD |
12:45 PM |
1:00 PM |
Textural Analysis of OCT En-Face Images Predicts Spatial Patterns of Retinal Neuronal Loss at the Macula |
Optic neuropathies |
524 |
Paper Session |
620 - Seattle Convention Center - Arch Building |
Eye Movements/Strabismus/Amblyopia/Neuro-Ophthalmology |
Presenter |
Jui-Kai Wang, Zhi Chen, honghai Zhang, Brian Woods, David Szanto, Brett Johnson, Edward Linton, Milan Sonka, Mark J. Kupersmith, Mona K. Garvin, Randy H. Kardon |
Thursday, May 9
| Zhi Chen |
1:15 PM |
1:30 PM |
Deep learning-based fluid segmentation in AMD OCT scans: Pretraining on a public dataset and fine-tuning for a specific setting |
Machine learning for image segmentation |
526 |
Paper Session |
Tahoma 2 - Seattle Convention Center - Arch Building |
Multidisciplinary Ophthalmic Imaging Group |
Presenter |
Zhi Chen, Bernardo Bolzani Bach, Andreas Wahle, Honghai Zhang, Elliott Sohn, Milan Sonka |
Thursday, May 9
| Robert F. Mullins, MS, PhD |
3:15 PM |
3:30 PM |
Heteroplasmy distribution in human retinal mitochondrial disease |
Mitochondrial function in healthy and diseased retina |
538 |
Paper Session |
606 - Seattle Convention Center - Arch Building |
Retinal Cell Biology |
Presenter |
Robert F. Mullins |