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Ophthalmology and Visual Sciences

Epithelial basement membrane dystrophy (map-dot-fingerprint dystrophy)

Epithelial basement membrane dystrophy (map-dot-fingerprint dystrophy)

Category(ies): Cornea
Contributor: Lorraine M. Provencher, MD
Photographer: Brice Critser, CRA

This patient had both Meesmann epithelial corneal dystrophy and striking epithelial basement membrane dystrophy (EBMD), neither of which were symptomatic.

Contributor: Meredith Baker, MD

72-year-old female with decrease in central visual acuity. Classic gray patches, fingerprint lines, map lines, dots, and cobblestone pattern in the corneal epithelium are seen on this photo.

Contributor: Thomas J.E. Clark, MD
Photographer: Carol Chan, CRA

This photo demonstrates classic "dots", which manifest as irregular round, oval, or comma-shaped, non-staining, putty-gray intraepithelial opacities. They represent intraepithelial pseudocysts containing cytoplasmic debris.


Weiss JS, Moller HU, Aldave AJ, et al. IC3D Classification of Corneal Dystrophies—Edition 2. Cornea. 2015;34:117-159.

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Ophthalmic Atlas Images by, The University of Iowa are licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.